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However, a full set of pluripotency-associated transcription factors may indeed result in the acquisition of a transient (at least partial) pluripotent intermediate during reprogramming.
In contrast to previous reports, the EBV-based plasmid system remained present and active inside the cells at all time points.
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Adult Stem Cells, also known as Mesenchymal Stem Cells, are cells that are undifferentiated and have the ability to not only replace dying cells but also regenerate damaged tissue.
We obtained induced neural stem cells (i NSC) 30 days after transfection.
In contrast to previous results, plasmid vectors as well as a residual expression of reprogramming factors remained detectable in all cell lines.
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We therefore established a reprogramming protocol based on vectors containing the Epstein-Barr virus (EBV)-derived ori P/EBNA1 as well as the defined expression factors Oct3/4, Sox2, Klf4, L-myc, Lin28, and a small hairpin directed against p53.Having an Omegle Chat Using Optional Features Using Proper Omegle Etiquette Community Q&A Are you looking for a new way to make friends online?Are you a student looking to connect with other people your age?In particular, adult stem cells seem to be an effective way of repairing cartilage in degenerated joints.Currently, the use of stem cells is considered investigational as it is not yet FDA approved for the treating any specific disease in the United States.